Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 3/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.81 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.81 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.81 |
| ▸ | STAT6 | P42226 | 1/20 | 0.81 |
| ▸ | GMNN | O75496 | 1/20 | 0.81 |
| ▸ | BLM | P54132 | 1/20 | 0.81 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.81 |
| ▸ | TP53 | P04637 | 3/20 | 0.77 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.72 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.72 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20626412 | 1.00 | PAX8 (1.00) | PAX8ADORA3ADORA2AADORA1TSHR | |
| SCHEMBL638142 | 1.00 | PAX8 (1.00) | PAX8ADORA3ADORA2AADORA1TSHR | |
| SCHEMBL20626411 | 1.00 | PAX8 (1.00) | PAX8ADORA3ADORA2AADORA1TSHR | |
| SCHEMBL29552250 | 1.00 | PAX8 (1.00) | PAX8ADORA3ADORA2AADORA1TSHR | |
| SCHEMBL638141 | 1.00 | PAX8 (1.00) | PAX8ADORA3ADORA2AADORA1TSHR | |
| SCHEMBL14713259 | 1.00 | PAX8 (1.00) | PAX8ADORA3ADORA2AADORA1TSHR | |
| SCHEMBL17824388 | 1.00 | PAX8 (1.00) | PAX8ADORA3ADORA2AADORA1TSHR | |
| SCHEMBL30411549 | 0.99 | PAX8 (0.98) | PAX8ADORA3ADORA2AADORA1TSHR | |
| SCHEMBL637914 | 0.90 | PAX8 (0.81) | PAX8ADORA3ADORA2AADORA1TSHR | |
| SCHEMBL639334 | 0.90 | PAX8 (0.81) | PAX8ADORA3ADORA2AADORA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229772-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2017-10-18 | — | — | EP | claimed |
| WO-2016091236-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-16 | — | — | WO | claimed |
| EP-3229772-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016091236-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-16 | — | — | WO | disclosed |