Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13973962 | 0.79 | MMP2 (0.36) | MMP2ANPEP | |
| SCHEMBL13688455 | 0.78 | MMP2 (0.40) | MMP2ANPEPTSHR | |
| SCHEMBL10137597 | 0.78 | MMP2 (0.40) | MMP2ANPEPTSHR | |
| SCHEMBL21515905 | 0.78 | MMP2 (0.40) | MMP2ANPEPTSHR | |
| SCHEMBL12401915 | 0.78 | MMP2 (0.40) | MMP2ANPEPTSHR | |
| SCHEMBL17973099 | 0.73 | MMP2 (0.60) | MMP2ANPEPMEN1KMT2A | |
| SCHEMBL2691165 | 0.73 | MMP2 (0.60) | MMP2ANPEPMEN1KMT2A | |
| SCHEMBL14569838 | 0.73 | MMP2 (0.37) | MMP2ANPEPTSHRMEN1KMT2A | |
| SCHEMBL13403397 | 0.73 | MMP2 (0.60) | MMP2ANPEPMEN1KMT2A | |
| SCHEMBL15121004 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365612-B2 | Caspase inhibitors | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-06-14 | — | — | US | disclosed |