Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.37 |
| ▸ | RAPGEF3 | O95398 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16158841 | 0.83 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL18720669 | 0.82 | RXFP1 (0.41) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL10150524 | 0.79 | STING1 (0.34) | STING1 | |
| SCHEMBL18720698 | 0.76 | RXFP1 (0.37) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL16158833 | 0.75 | KMT2A (0.35) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL18720658 | 0.74 | RXFP1 (0.36) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL16158849 | 0.72 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL17826621 | 0.71 | LMNA (0.47) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL10239776 | 0.69 | STING1 (0.76) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL10150526 | 0.69 | STING1 (0.56) | PDE4APDE4BPDE4CPDE4DSTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365605-B2 | Cyclic nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2016-06-14 | — | — | US | disclosed |