Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | GJB2 | P29033 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.37 |
| ▸ | CDC25B | P30305 | 7/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27064271 | 0.91 | SSTR1 (0.47) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL22168445 | 0.91 | SSTR1 (0.47) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL17826458 | 0.85 | NT5E (0.36) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL16367548 | 0.82 | SLC6A2 (0.35) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL26452998 | 0.81 | SELP (0.37) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL29827603 | 0.80 | SSTR1 (0.47) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL19400393 | 0.80 | PTPN1 (0.49) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL26453858 | 0.79 | PTPN1 (0.55) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13377703 | 0.77 | SSTR1 (0.44) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL22168496 | 0.77 | GJB2 (0.41) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700532-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2017-07-11 | — | — | US | disclosed |
| US-9365496-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2016-06-14 | — | — | US | disclosed |