Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17577087 | 1.00 | ADORA2A (0.46) | ADORA2AADORA1ADORA3BCHEMALT1 | |
| SCHEMBL17564680 | 0.85 | BCHE (0.46) | ADORA2AADORA1ADORA3BCHEMALT1 | |
| SCHEMBL17874527 | 0.83 | ADORA2A (0.41) | ADORA2AADORA1ADORA3BCHEADORA2B | |
| SCHEMBL17563718 | 0.81 | ADORA2A (0.43) | ADORA2AADORA1ADORA3BCHEMALT1 | |
| SCHEMBL31436060 | 0.78 | STK17B (0.58) | ADORA2AADORA1BCHEADORA2BTDP1 | |
| SCHEMBL17563733 | 0.77 | STK17B (0.51) | ADORA2AADORA1ADORA3BCHEMALT1 | |
| SCHEMBL17826072 | 0.76 | BCHE (0.44) | ADORA2AADORA1ADORA3BCHEMALT1 | |
| SCHEMBL17564597 | 0.76 | LMNA (0.51) | ADORA2AADORA1ADORA3BCHEMALT1 | |
| SCHEMBL9526152 | 0.76 | KMT2A (0.39) | MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL34362 | 0.75 | TDP1 (0.58) | MALT1TDP1MAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365676-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2016-06-14 | — | — | US | disclosed |