Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 7/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14686430 | 0.89 | PRCP (0.76) | PRCPLMNATSHRCCR3 | |
| SCHEMBL14686464 | 0.89 | PRCP (0.76) | PRCPLMNAALOX15TSHRMAPK1 | |
| SCHEMBL14686541 | 0.89 | PRCP (1.00) | PRCPLMNAALOX15TSHRMAPK1 | |
| SCHEMBL14701329 | 0.81 | PRCP (0.86) | PRCPGRM5CNR1 | |
| SCHEMBL14749338 | 0.81 | PRCP (0.65) | PRCP | |
| SCHEMBL14749335 | 0.80 | PRCP (0.64) | PRCP | |
| SCHEMBL12184064 | 0.80 | PRCP (0.83) | PRCPCNR1 | |
| SCHEMBL12183983 | 0.80 | PRCP (0.64) | PRCPMAPK1NAMPT | |
| SCHEMBL12186038 | 0.79 | PRCP (0.63) | PRCPLMNAALOX15TSHRMAPK1 | |
| SCHEMBL12185602 | 0.77 | PRCP (0.70) | PRCPTSHRGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365539-B2 | Prolylcarboxypeptidase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-06-14 | — | — | US | disclosed |