Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18197823 | 0.82 | PTPN2 (0.38) | PTPN2PTPN1CDC25BIDO1 | |
| SCHEMBL3635614 | 0.82 | IDO1 (0.40) | PTPN2PTPN1CDC25BIDO1 | |
| SCHEMBL24465058 | 0.74 | PTPN2 (0.35) | PTPN2PTPN1CDC25BIDO1 | |
| SCHEMBL17827002 | 0.71 | — | — | |
| SCHEMBL18197791 | 0.70 | IDO1 (0.42) | PTPN2PTPN1CDC25BIDO1 | |
| SCHEMBL8443626 | 0.68 | PTPN2 (0.35) | PTPN2PTPN1CDC25B | |
| SCHEMBL8443084 | 0.63 | MAPT (0.40) | PTPN2PTPN1CDC25B | |
| SCHEMBL2579044 | 0.63 | MAPT (0.40) | PTPN2PTPN1CDC25B | |
| SCHEMBL8443621 | 0.63 | MAPT (0.40) | PTPN2PTPN1CDC25B | |
| SCHEMBL9205144 | 0.62 | PTPN2 (0.38) | PTPN2PTPN1CDC25BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567035-A1 | N-SUBSTITUTED 2,5-DIOXO-AZOLINE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Canbas Co. Ltd. (JP) | 2019-11-13 | — | — | EP | disclosed |
| EP-3088397-A1 | COMPOUNDS THAT ABROGATE THE CELL CYCLE G2 CHECKPOINT FOR USE IN THE TREATMENT OF CANCER | Canbas Co. Ltd. (JP) | 2016-11-02 | — | — | EP | disclosed |
| EP-2152692-B1 | COMPOUNDS WITH ANTI-CANCER ACTIVITY | CANBAS CO LTD (JP) | 2016-06-15 | — | — | EP | disclosed |