Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443084 | 1.00 | MAPT (0.40) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL8442749 | 1.00 | MAPT (0.40) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL8443621 | 1.00 | MAPT (0.40) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL8438882 | 0.92 | ALDH1A1 (0.51) | MAPTTDP1ALDH1A1THRBCYP2D6 | |
| SCHEMBL5722122 | 0.92 | ALDH1A1 (0.51) | MAPTTDP1ALDH1A1THRBCYP2D6 | |
| SCHEMBL5970520 | 0.92 | ALDH1A1 (0.51) | MAPTTDP1ALDH1A1THRBCYP2D6 | |
| SCHEMBL8439720 | 0.92 | ALDH1A1 (0.51) | MAPTTDP1ALDH1A1THRBCYP2D6 | |
| SCHEMBL187581 | 0.92 | ALDH1A1 (0.51) | MAPTTDP1ALDH1A1THRBCYP2D6 | |
| SCHEMBL1535496 | 0.89 | ALDH1A1 (0.49) | MAPTTDP1ALDH1A1THRBCYP3A4 | |
| SCHEMBL1535486 | 0.86 | ALDH1A1 (0.42) | MAPTTDP1ALDH1A1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363460-A1 | EPOXY-AMINE COMPOSITIONS EMPLOYING UNSATURATED IMIDES. | LOCTITE CORP (US) | 1990-04-18 | — | — | EP | claimed |
| WO-1989008122-A1 | EPOXY-AMINE COMPOSITIONS EMPLOYING UNSATURATED IMIDES | LOCTITE CORPORATION (US) | 1989-09-08 | — | — | WO | claimed |
| US-8048489-B2 | Compositions comprising biscitraconimide, bisitaconimide, and/or citraconimido-itaconimide | LANXESS DEUTSCHLAND GMBH (DE) | 2011-11-01 | — | — | US | disclosed |
| EP-2018401-B1 | COMPOSITIONS COMPRISING BISCITRACONIMIDE, BISITACONIMIDE, AND/OR CITRACONIMIDO-ITACONIMIDE | FLEXSYS BV (NL) | 2010-01-27 | — | — | EP | disclosed |
| US-20090186158-A1 | COMPOSITIONS COMPRISING BISCITRACONIMIDE, BISITACONIMIDE, AND/OR CITRACONIMIDO-ITACONIMIDE | LANXESS DEUTSCHLAND GMBH (DE) | 2009-07-23 | — | — | US | disclosed |
| EP-2018401-A2 | COMPOSITIONS COMPRISING BISCITRACONIMIDE, BISITACONIMIDE, AND/OR CITRACONIMIDO-ITACONIMIDE | Flexsys B.V. (NL) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007134948-A2 | COMPOSITIONS COMPRISING BISCITRACONIMIDE, BISITACONIMIDE, AND/OR CITRACONIMIDO-ITACONIMIDE | FLEXSYS B.V. (NL) | 2007-11-29 | — | — | WO | disclosed |
| EP-0495544-B1 | Process for the synthesis of citraconimides | AKZO NOBEL NV (NL) | 1999-04-07 | — | — | EP | disclosed |
| EP-0273731-A1 | Imide compound and composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-07-06 | — | — | EP | disclosed |