Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30250666 | 0.91 | TP53 (0.61) | TP53TDP1ALOX15HSD17B10MAPT | |
| SCHEMBL1758394 | 0.91 | TP53 (0.61) | TP53TDP1ALOX15HSD17B10MAPT | |
| SCHEMBL31547677 | 0.83 | TDP1 (0.52) | TP53TDP1ALOX15MAPTALDH1A1 | |
| SCHEMBL6243491 | 0.83 | ALDH1A1 (0.72) | TP53TDP1ALOX15HSD17B10MAPT | |
| SCHEMBL3043421 | 0.83 | TDP1 (0.52) | TP53TDP1ALOX15MAPTALDH1A1 | |
| SCHEMBL5088743 | 0.81 | TP53 (0.56) | TP53TDP1ALOX15HSD17B10MAPT | |
| SCHEMBL6068072 | 0.80 | TP53 (0.54) | TP53TDP1CYP1A2CYP2C19TRPA1 | |
| SCHEMBL14455084 | 0.79 | ESR2 (0.63) | TP53TDP1CYP1A2CYP2C19ESR1 | |
| SCHEMBL1828915 | 0.78 | TP53 (0.52) | TP53TDP1ALOX15HSD17B10MAPT | |
| SCHEMBL29362536 | 0.78 | TP53 (0.52) | TP53TDP1ALOX15HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325225-B1 | Complex aryl copolymer compounds and polymer light emitting devices made by using the same | SUMITOMO CHEMICAL CO (JP) | 2016-06-15 | — | — | EP | disclosed |