Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1196448 | 0.85 | ALDH1A1 (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28369299 | 0.81 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17036679 | 0.80 | MEN1 (0.42) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL819340 | 0.76 | TLR4 (0.39) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22855358 | 0.75 | ALDH1A1 (0.44) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1783162 | 0.74 | — | — | |
| SCHEMBL24249958 | 0.74 | TLR4 (0.49) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1141761 | 0.74 | TLR4 (0.49) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17118109 | 0.74 | TLR4 (0.49) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL19552512 | 0.74 | ALDH1A1 (0.46) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031324-A2 | TRICYCLIC KINASE INHIBITORS | AbbVie Inc. (US) | 2016-06-15 | — | — | EP | disclosed |