Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25574499 | 1.00 | ALOX5AP (0.35) | ALOX5APFEN1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL25573802 | 0.88 | CHKA (0.34) | ALOX5APFEN1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL21677977 | 0.85 | GRM2 (0.37) | ALOX5APFEN1RPS6KB1KIF11HTR2A | |
| SCHEMBL21677978 | 0.85 | PDE3B (0.40) | KIF11HTR2AGRM2CHKA | |
| SCHEMBL17827771 | 0.85 | GPR84 (0.40) | ALOX5APFEN1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL17827767 | 0.84 | GRM2 (0.37) | ALOX5APFEN1F10KIF11GRM2 | |
| SCHEMBL17827805 | 0.83 | RPS6KB1 (0.37) | RPS6KB1F10ATM | |
| SCHEMBL23643404 | 0.81 | CYP3A4 (0.44) | CYP17A1CYP11B1CYP11B2KIF11CHKA | |
| SCHEMBL26383586 | 0.81 | GRIN1 (0.42) | ALOX5APFEN1KIF11HTR2AGRM2 | |
| SCHEMBL18458755 | 0.77 | TAAR1 (0.53) | ALOX5APFEN1CYP17A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9404038-B2 | Cyclopropyl-bearing liquid crystal compounds and mixtures | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-08-02 | — | — | US | disclosed |
| US-9404038-B2 | Cyclopropyl-bearing liquid crystal compounds and mixtures | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-08-02 | — | — | US | disclosed |
| US-20160168461-A1 | CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-06-16 | — | — | US | disclosed |
| US-20160168461-A1 | CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-06-16 | — | — | US | disclosed |