Sugi Predict

Sugi Predict / Compounds / SCHEMBL17828588

SCHEMBL17828588

SCHEMBL17828588

CCCCN(CCC[Si](C)(O)OC)C(=O)NCCC[Si](OC)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 1/20 0.33
▸ CA12 O43570 2/20 0.32
▸ CA1 P00915 2/20 0.32
▸ CA9 Q16790 2/20 0.32
▸ LMNA P02545 2/20 0.31
▸ ACHE P22303 1/20 0.30
▸ MMP1 P03956 1/20 0.30
▸ MMP2 P08253 1/20 0.30
▸ MMP3 P08254 1/20 0.30
▸ MMP8 P22894 1/20 0.30
▸ TSHR P16473 2/20 0.30
▸ HDAC1 Q13547 1/20 0.30
▸ HDAC6 Q9UBN7 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19929282 0.92 EPHX1 (0.39) EPHX1CA12CA1CA9LMNA
SCHEMBL19929284 0.88 EPHX1 (0.45) EPHX1CA12CA1CA9LMNA
SCHEMBL2565754 0.86 CA14 (0.33) EPHX1TSHR
SCHEMBL3359618 0.85 EPHX1 (0.45) EPHX1LMNAACHE
SCHEMBL2616732 0.83 EPHX1 (0.37) EPHX1CA12CA9LMNAACHE
SCHEMBL22574055 0.82 CA12 (0.38) EPHX1CA12CA1CA9LMNA
SCHEMBL17133217 0.81 EPHX1 (0.44) EPHX1ACHEHSD17B10
SCHEMBL17133208 0.81 ACHE (0.35) EPHX1LMNAACHEMMP2ALDH1A1
SCHEMBL21924930 0.81 EPHX1 (0.30) EPHX1
SCHEMBL13907613 0.78 EPHX1 (0.34) EPHX1LMNAACHETSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180066165-A1 HIGH-SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES GELEST, INC. 2018-03-08 — — US disclosed
US-9879159-B2 High-speed moisture-cure hybrid siloxane/silsesquioxane-urethane and siloxane/silsesquioxane-epoxy systems with adhesive properties GELEST TECHNOLOGIES, INC. (US) 2018-01-30 — — US disclosed
US-20160168429-A1 HIGH-SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES GELEST, INC. 2016-06-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180066165-A1 HIGH-SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES PCNA, ICAM1, CCNO EPHX1 46/4885CA12 500/4885CA1 219/4885
US-20160168429-A1 HIGH-SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES PCNA, ICAM1, CCNO EPHX1 46/4885CA12 500/4885CA1 219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.