Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19713069 | 0.93 | ENPP2 (0.53) | ENPP2RAD51KDM4ERAB9AAPEX1 | |
| SCHEMBL17830394 | 0.93 | ENPP2 (0.53) | ENPP2RAD51KDM4ERAB9AAPEX1 | |
| SCHEMBL19726891 | 0.92 | ENPP2 (0.44) | ENPP2RAD51KDM4ERAB9AAPEX1 | |
| SCHEMBL17830249 | 0.91 | ENPP2 (0.53) | ENPP2RAD51KDM4ERAB9AAPEX1 | |
| SCHEMBL19713037 | 0.91 | ENPP2 (0.53) | ENPP2RAD51KDM4ERAB9AAPEX1 | |
| SCHEMBL22607607 | 0.91 | ENPP2 (0.43) | ENPP2RAD51KDM4ERAB9AAPEX1 | |
| SCHEMBL17830396 | 0.89 | ENPP2 (0.48) | ENPP2RAD51KDM4ERAB9AAPEX1 | |
| SCHEMBL17830248 | 0.87 | ENPP2 (0.47) | ENPP2RAD51KDM4ERAB9AAPEX1 | |
| SCHEMBL14358597 | 0.86 | ENPP2 (0.69) | ENPP2RAD51KDM4ERAB9AAPEX1 | |
| SCHEMBL14358601 | 0.86 | ENPP2 (0.69) | ENPP2RAD51KDM4ERAB9AAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094897-A1 | COMPOSITIONS AND METHODS RELATING TO THE TREATMENT OF CANCER, AUTOIMMUNE DISEASE, AND NEURODEGENERATIVE DISEASE | THE JACKSON LABORATORY (US) | 2016-06-16 | — | — | WO | disclosed |