Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830432 | 0.85 | ENPP2 (0.68) | ENPP2RAD51ALDH1A1APEX1GSTO1 | |
| SCHEMBL19726901 | 0.79 | ENPP2 (0.60) | ENPP2RAD51PKMALDH1A1APEX1 | |
| SCHEMBL7825431 | 0.78 | ENPP2 (0.78) | ENPP2RAD51PKMCYP2C19ALDH1A1 | |
| SCHEMBL7550076 | 0.78 | ENPP2 (0.78) | ENPP2RAD51PKMCYP2C19ALDH1A1 | |
| SCHEMBL19726891 | 0.74 | ENPP2 (0.44) | ENPP2RAD51PKMALDH1A1APEX1 | |
| SCHEMBL19726905 | 0.74 | ENPP2 (0.46) | ENPP2RAD51PKMALDH1A1APEX1 | |
| SCHEMBL19733689 | 0.73 | ENPP2 (0.53) | ENPP2RAD51ALDH1A1APEX1GSTO1 | |
| SCHEMBL17830249 | 0.73 | ENPP2 (0.53) | ENPP2RAD51PKMALDH1A1APEX1 | |
| SCHEMBL19713037 | 0.73 | ENPP2 (0.53) | ENPP2RAD51PKMALDH1A1APEX1 | |
| SCHEMBL9321055 | 0.71 | ENPP2 (0.91) | ENPP2RAD51ALDH1A1APEX1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094897-A1 | COMPOSITIONS AND METHODS RELATING TO THE TREATMENT OF CANCER, AUTOIMMUNE DISEASE, AND NEURODEGENERATIVE DISEASE | THE JACKSON LABORATORY (US) | 2016-06-16 | — | — | WO | disclosed |