SCHEMBL17831016

SCHEMBL17831016

Cc1cc(C)cc(N2c3ccccc3N(c3ccccc3C)C2C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.37
▸ MAPT P10636 5/20 0.37
▸ MEN1 O00255 4/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ KDM4E B2RXH2 4/20 0.36
▸ LMNA P02545 2/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ HPGD P15428 3/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ MGLL Q99685 1/20 0.34
▸ GFER P55789 1/20 0.33
▸ ADRB1 P08588 1/20 0.33
▸ HSD17B10 Q99714 3/20 0.32
▸ GAA P10253 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ HKDC1 Q2TB90 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21074291 1.00 ALDH1A1 (0.37) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL19999703 1.00 ALDH1A1 (0.37) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL19749036 0.91 ALDH1A1 (0.42) ALDH1A1MAPTKDM4ELMNANPSR1
SCHEMBL25518180 0.86 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL22781105 0.85 ALDH1A1 (0.44) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL15397099 0.84 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL16220756 0.84 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL12643067 0.84 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL21074282 0.82 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL19999700 0.82 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3492480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-10-20 — — EP disclosed
EP-3492480-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-06-05 — — EP disclosed
US-10290817-B2 Luminescent diaza-monoaza-and benzimidazole metal carbene complexes for use in electronic devices such as OLEDs UDC IRELAND LIMITED (IE) 2019-05-14 — — US disclosed
US-20160172606-A1 LUMINESCENT DIAZA-MONOAZA-AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2016-06-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160172606-A1 LUMINESCENT DIAZA-MONOAZA-AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS OCIAD1, OCIAD2, OXA1L ALDH1A1 857/4885MAPT 2778/4885MEN1 3016/4885
US-10290817-B2 Luminescent diaza-monoaza-and benzimidazole metal carbene complexes for use in electronic devices such as OLEDs OCIAD1, OCIAD2, OXA1L ALDH1A1 857/4885MAPT 2778/4885MEN1 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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