Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12121020 | 0.90 | CYP3A4 (0.46) | CYP3A4ACHEGLO1HPGDALDH1A1 | |
| SCHEMBL1036031 | 0.86 | CYP3A4 (0.59) | CYP3A4ACHEGLO1HPGDALDH1A1 | |
| SCHEMBL26741039 | 0.85 | POLB (0.47) | CYP3A4ACHEGLO1HPGDALDH1A1 | |
| SCHEMBL12554705 | 0.82 | CYP3A4 (0.52) | CYP3A4ACHEGLO1HPGDALDH1A1 | |
| SCHEMBL22996828 | 0.81 | CYP3A4 (0.47) | CYP3A4ACHEGLO1HPGDALDH1A1 | |
| SCHEMBL25747027 | 0.81 | CYP3A4 (0.47) | CYP3A4ACHEGLO1HPGDALDH1A1 | |
| SCHEMBL17419113 | 0.81 | CYP3A4 (0.47) | CYP3A4ACHEGLO1HPGDALDH1A1 | |
| SCHEMBL17781586 | 0.80 | CYP3A4 (0.46) | CYP3A4ACHEGLO1HPGDALDH1A1 | |
| SCHEMBL22889954 | 0.80 | CYP3A4 (0.46) | CYP3A4ACHEGLO1HPGDALDH1A1 | |
| SCHEMBL10174735 | 0.80 | CYP3A4 (0.46) | CYP3A4ACHEGLO1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656995-B2 | Triazine derivative | CARNA BIOSCIENCES, INC. (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20160168122-A1 | NOVEL TRIAZINE DERIVATIVE | CARNA BIOSCIENCES, INC. (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168122-A1 | NOVEL TRIAZINE DERIVATIVE | CBR3, HDAC3, SSTR3 | CYP3A4 642/4885ACHE 4058/4885GLO1 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.