Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL8614869 | 0.85 | FFAR3 (0.53) | ALDH1A1LMNACYP1A2EPHX1KDM4E | |
| Methylcyclopentane SCHEMBL27727030 | 0.85 | FFAR3 (0.53) | ALDH1A1LMNACYP1A2EPHX1KDM4E | |
| Propionic Acid SCHEMBL4088363 | 0.85 | FFAR3 (0.53) | ALDH1A1LMNACYP1A2EPHX1KDM4E | |
| Glycolic Acid SCHEMBL9935780 | 0.83 | CYP1A2 (0.44) | TSHRALDH1A1LMNACYP1A2EPHX1 | |
| SCHEMBL8964234 | 0.82 | EPHX1 (0.46) | TSHRALDH1A1LMNACYP1A2EPHX1 | |
| SCHEMBL5728127 | 0.82 | EPHX1 (0.46) | TSHRALDH1A1LMNACYP1A2EPHX1 | |
| Bicarbonate SCHEMBL17847302 | 0.82 | EPHX1 (0.50) | TSHRALDH1A1CYP1A2EPHX1SMN1; SMN2 | |
| Bicarbonate SCHEMBL8913592 | 0.82 | EPHX1 (0.50) | TSHRALDH1A1CYP1A2EPHX1SMN1; SMN2 | |
| Bicarbonate SCHEMBL4695324 | 0.82 | EPHX1 (0.50) | TSHRALDH1A1CYP1A2EPHX1SMN1; SMN2 | |
| Acetic Acid SCHEMBL4093239 | 0.79 | EPHX1 (0.48) | TSHRALDH1A1CYP1A2EPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118229-A1 | 2-ARYLMETHYLAZETIDINE-CARBAPENEM-3-CARBOXYLIC ACID ESTER DERIVATIVE OR ITS SALT, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KUKJE PHARM. IND. CO., LTD. (KR) | 2011-05-19 | — | — | US | disclosed |
| EP-0808315-B1 | CARBAPENEM-3-CARBOXYLIC ACID ESTER DERIVATIVES | WYETH LEDERLE JAPAN LTD (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5886172-A | ORAL PRODRUG READILY ABSORPED IN THE DIGESTIVE TRACT AND HYDROLYZED; BIOAVAILABIITY; STRONG ANTIBACTERIAL ACTIVITY ESPECIALLY AGAINST STAPHYLOCOCCUS; STREPTOCOCCUS, KLEBSIELLA AND PROTEUS | LEDERLE (JAPAN) LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0808315-A1 | CARBAPENEM-3-CARBOXYLIC ACID ESTER DERIVATIVES | LEDERLE (JAPAN), Ltd. (JP) | 1997-11-26 | — | — | EP | disclosed |
| WO-1997021712-A1 | CARBAPENEM-3-CARBOXYLIC ACID ESTER DERIVATIVES | LEDERLE (JAPAN), LTD. (JP) | 1997-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118229-A1 | 2-ARYLMETHYLAZETIDINE-CARBAPENEM-3-CARBOXYLIC ACID ESTER DERIVATIVE OR ITS SALT, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CYP2C19, CYP2C9, SCN9A | TSHR 4168/4885ALDH1A1 1407/4885LMNA 1267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.