Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911666 | 0.77 | CA1 (0.36) | CA1CA2CA9 | |
| SCHEMBL23449963 | 0.73 | CA1 (0.30) | CA1CA2CA9 | |
| SCHEMBL20169089 | 0.73 | CA1 (0.30) | CA1CA2CA9 | |
| SCHEMBL1521576 | 0.72 | CA1 (0.56) | CA1CA2CA9 | |
| SCHEMBL20457638 | 0.72 | CA1 (0.56) | CA1CA2CA9 | |
| SCHEMBL15694522 | 0.72 | CA1 (0.56) | CA1CA2CA9 | |
| SCHEMBL17822617 | 0.72 | CA1 (0.56) | CA1CA2CA9 | |
| SCHEMBL12437304 | 0.70 | CA2 (0.35) | CA1CA2CA9 | |
| SCHEMBL27410591 | 0.70 | CA2 (0.35) | CA1CA2CA9 | |
| SCHEMBL23408919 | 0.70 | CA1 (0.35) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016091698-A1 | 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2,7-DIONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2016-06-16 | — | — | WO | disclosed |