SCHEMBL17831815

SCHEMBL17831815

OC(C(C1CC2CCC1C2)C(F)(F)F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17829492 0.84 HPGD (0.43) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL1217572 0.76 LMNA (0.35) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL27549560 0.72 LMNA (0.34) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL16900287 0.72 HPGD (0.40) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL16900481 0.72 HPGD (0.37) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL7184444 0.71 HPGD (0.42) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL3821014 0.71 HPGD (0.42) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL24906563 0.67 HPGD (0.40) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL14646057 0.67 HPGD (0.47) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL3345713 0.67 HPGD (0.47) LMNAHPGDSMN1; SMN2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160168296-A1 POLYMER, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-06-16 US disclosed