Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 5/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 12/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829647 | 0.86 | CTNNB1 (0.46) | CTNNB1TCF7L2 | |
| SCHEMBL17831897 | 0.81 | CCR4 (0.44) | CCR4TMEM97SIGMAR1CHRM2ADRB1 | |
| SCHEMBL17829812 | 0.80 | CCR4 (0.56) | CCR4 | |
| SCHEMBL17829565 | 0.78 | CCR4 (0.58) | CCR4 | |
| SCHEMBL17829804 | 0.77 | CCR4 (0.64) | CCR4 | |
| SCHEMBL17829619 | 0.75 | CCR4 (0.57) | CCR4 | |
| SCHEMBL17829618 | 0.74 | CCR4 (0.53) | CCR4 | |
| SCHEMBL17833178 | 0.74 | CCR4 (0.55) | CCR4TMEM97SIGMAR1CHRM2ADRA2A | |
| SCHEMBL17829857 | 0.74 | CCR4 (0.53) | CCR4 | |
| SCHEMBL17829825 | 0.74 | CCR4 (0.54) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |