Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 8/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 2/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | MATK | P42679 | 1/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.39 |
| ▸ | BMX | P51813 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.39 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829651 | 0.93 | CCR4 (0.39) | CCR4CACNA2D1FLT3MELK | |
| SCHEMBL17833263 | 0.87 | CCR4 (0.51) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829794 | 0.82 | CCR4 (0.44) | CCR4CACNA2D1FLT3MELKLYN | |
| SCHEMBL17829804 | 0.81 | CCR4 (0.64) | CCR4CACNA2D1FLT3MELKLYN | |
| SCHEMBL17829852 | 0.80 | CCR4 (0.52) | CCR4CACNA2D1FLT3MELKLYN | |
| SCHEMBL17830140 | 0.79 | CCR4 (0.54) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829572 | 0.79 | CCR4 (0.47) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829618 | 0.78 | CCR4 (0.53) | CCR4CACNA2D1FLT3MELK | |
| SCHEMBL17829812 | 0.78 | CCR4 (0.56) | CCR4CACNA2D1FLT3MELKLYN | |
| SCHEMBL17833269 | 0.78 | CCR4 (0.41) | CCR4CACNA2D1FLT3MELKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |