Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 6/20 | 0.51 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833017 | 0.87 | CCR4 (0.47) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829648 | 0.84 | POLB (0.46) | CACNA2D1FLT3HTR1AHTR6 | |
| SCHEMBL17829620 | 0.81 | CCR4 (0.76) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829638 | 0.81 | CCR4 (0.48) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829807 | 0.81 | CCR4 (0.72) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829627 | 0.80 | CCR4 (0.63) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829618 | 0.80 | CCR4 (0.53) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829651 | 0.80 | CCR4 (0.39) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829828 | 0.79 | CCR4 (0.59) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829702 | 0.79 | CCR4 (0.56) | CCR4CACNA2D1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |