Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829910 | 0.96 | SYK (0.44) | SYKCTSKKCNH2ALDH1A1KDM4E | |
| SCHEMBL17833283 | 0.93 | SYK (0.40) | SYKCTSKKCNH2ALDH1A1KDM4E | |
| SCHEMBL17833238 | 0.92 | TNKS (0.41) | SYKCTSKKCNH2ALDH1A1KDM4E | |
| SCHEMBL17833277 | 0.92 | SYK (0.37) | SYKCTSKKCNH2ALDH1A1KDM4E | |
| SCHEMBL17833161 | 0.91 | KMT2A (0.40) | SYKCTSKKCNH2ALDH1A1KDM4E | |
| SCHEMBL17829839 | 0.89 | RAD52 (0.50) | SYKKCNH2ALDH1A1KDM4EGAA | |
| SCHEMBL17833280 | 0.89 | SYK (0.37) | SYKCTSKKCNH2ALDH1A1KDM4E | |
| SCHEMBL17833279 | 0.89 | CTNNB1 (0.37) | SYKCTSKKCNH2ALDH1A1KDM4E | |
| SCHEMBL17833150 | 0.87 | CYP1A2 (0.41) | ALDH1A1KMT2AMAPK1 | |
| SCHEMBL17829964 | 0.86 | CYP1A2 (0.37) | SYKALDH1A1KDM4EGAARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |