Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833235 | 0.92 | SYK (0.43) | SYKKMT2ARAD52CTNNB1TCF7L2 | |
| SCHEMBL17829910 | 0.92 | SYK (0.44) | SYKKMT2ARAD52KDM4EALDH1A1 | |
| SCHEMBL17833154 | 0.90 | SYK (0.37) | SYKKMT2ARAD52KDM4EALDH1A1 | |
| SCHEMBL17829841 | 0.89 | RAD52 (0.50) | KMT2ARAD52ALDH1A1KCNH2MEN1 | |
| SCHEMBL17833283 | 0.89 | SYK (0.40) | SYKKMT2ARAD52CTNNB1TCF7L2 | |
| SCHEMBL17833238 | 0.88 | TNKS (0.41) | SYKKMT2ARAD52CTNNB1TCF7L2 | |
| SCHEMBL17833161 | 0.87 | KMT2A (0.40) | SYKKMT2ARAD52CTNNB1TCF7L2 | |
| SCHEMBL17833162 | 0.85 | SYK (0.39) | SYKKMT2ARAD52CTNNB1TCF7L2 | |
| SCHEMBL17833274 | 0.85 | SYK (0.39) | SYKKMT2ARAD52CTNNB1TCF7L2 | |
| SCHEMBL17833278 | 0.84 | CYP11B2 (0.38) | SYKKMT2ARAD52CTNNB1TCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |