Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17831900 | 0.89 | RAD52 (0.54) | SYKACP1KMT2ARAD52ALDH1A1 | |
| SCHEMBL17833162 | 0.86 | SYK (0.39) | SYKACP1KMT2ARAD52ABCG2 | |
| SCHEMBL17829847 | 0.84 | RAD52 (0.58) | SYKACP1KMT2ARAD52ALDH1A1 | |
| SCHEMBL17833274 | 0.79 | SYK (0.39) | SYKACP1KMT2ARAD52ABCG2 | |
| SCHEMBL17829956 | 0.78 | SYK (0.47) | SYKKMT2ARAD52ALDH1A1KDM4E | |
| SCHEMBL17831892 | 0.77 | RAD52 (0.63) | ACP1KMT2ARAD52ABCG2ALDH1A1 | |
| SCHEMBL17829975 | 0.76 | RAD52 (0.48) | SYKKMT2ARAD52ALDH1A1MAPK1 | |
| SCHEMBL17829814 | 0.76 | RAD52 (0.49) | SYKKMT2ARAD52ALDH1A1MAPK1 | |
| SCHEMBL17831887 | 0.76 | CCR4 (0.55) | — | |
| SCHEMBL17829910 | 0.74 | SYK (0.44) | SYKACP1KMT2ARAD52ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |