Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.36 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833274 | 0.93 | SYK (0.39) | SYKKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL17829956 | 0.92 | SYK (0.47) | SYKKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL17829814 | 0.90 | RAD52 (0.49) | SYKALDH1A1KMT2ARAD52KCNH2 | |
| SCHEMBL17829910 | 0.89 | SYK (0.44) | SYKKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL17833241 | 0.86 | SYK (0.42) | SYKKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL17833235 | 0.85 | SYK (0.43) | SYKKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL17833277 | 0.85 | SYK (0.37) | SYKKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL17833283 | 0.84 | SYK (0.40) | SYKKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL17833278 | 0.84 | CYP11B2 (0.38) | SYKKDM4EALDH1A1KMT2ARAD52 | |
| SCHEMBL17829885 | 0.83 | SYK (0.36) | SYKKMT2ARAD52CTSKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |