SCHEMBL17833256

SCHEMBL17833256

Cc1ccc(C(=O)CN2C(=O)C(=O)N(Cc3ccccc3)C2=O)s1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.63
KMT2A Q03164 5/20 0.57
RAB9A P51151 1/20 0.55
LMNA P02545 4/20 0.51
ALDH1A1 P00352 5/20 0.49
S1PR2 O95136 1/20 0.46
GAA P10253 1/20 0.45
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
F2 P00734 1/20 0.45
PLG P00747 1/20 0.45
ELANE P08246 1/20 0.45
CTSG P08311 1/20 0.45
CMA1 P23946 1/20 0.45
CTRC Q99895 1/20 0.45
DUSP3 P51452 1/20 0.44
PTPN5 P54829 1/20 0.44
PTPN11 Q06124 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17822175 0.86 KMT2A (0.58) MAPTKMT2ARAB9ALMNAALDH1A1
SCHEMBL17822176 0.78 MAPT (0.81) MAPTKMT2ARAB9ALMNAALDH1A1
SCHEMBL8143584 0.76 KMT2A (0.76) MAPTKMT2ARAB9AALDH1A1CYP2C19
SCHEMBL13793073 0.73 ELANE (0.82) MAPTKMT2ARAB9AALDH1A1MEN1
SCHEMBL9323818 0.73 KMT2A (0.76) MAPTKMT2ARAB9AALDH1A1MEN1
SCHEMBL17833255 0.73 MAPT (0.78) MAPTKMT2ARAB9ALMNAALDH1A1
SCHEMBL17833116 0.72 MAPT (0.76) MAPTKMT2ARAB9ALMNAALDH1A1
SCHEMBL17835171 0.72 MAPT (0.76) MAPTKMT2ARAB9ALMNAALDH1A1
SCHEMBL20277547 0.72 MAPT (0.74) MAPTKMT2ARAB9ALMNAALDH1A1
SCHEMBL17833180 0.71 MAPT (0.73) MAPTKMT2ARAB9ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016094690-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094682-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed