Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 15/20 | 0.72 |
| ▸ | TNKS2 | Q9H2K2 | 15/20 | 0.72 |
| ▸ | PARP1 | P09874 | 12/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.64 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833160 | 0.87 | TNKS (0.68) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL17829660 | 0.87 | TNKS (0.72) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL17829758 | 0.86 | TNKS (0.70) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL17833163 | 0.85 | TNKS (0.69) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17829754 | 0.85 | TNKS (0.69) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL15775476 | 0.84 | TNKS (1.00) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17833266 | 0.84 | TNKS (0.64) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL17829691 | 0.84 | TNKS (0.76) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL17829756 | 0.84 | TNKS (0.74) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL15775325 | 0.83 | TNKS (1.00) | TNKSTNKS2PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |