Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 17/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 17/20 | 1.00 |
| ▸ | PARP1 | P09874 | 12/20 | 1.00 |
| ▸ | PARP2 | Q9UGN5 | 5/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775325 | 0.89 | TNKS (1.00) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL15775474 | 0.87 | TNKS (1.00) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL15775251 | 0.87 | TNKS (1.00) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL15775692 | 0.87 | TNKS (1.00) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL7569320 | 0.87 | TNKS (1.00) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL15775949 | 0.87 | TNKS (1.00) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17829611 | 0.84 | TNKS (0.72) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17833265 | 0.84 | TNKS (0.72) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL7566607 | 0.84 | TNKS (1.00) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17829691 | 0.84 | TNKS (0.76) | TNKSTNKS2PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103880761-B | The method of one pot process 4 (3H)-Quinazol derivative is eliminated by cyclization | TIANJIN UNIVERSITY (CN) | 2015-07-29 | — | — | CN | disclosed |
| CN-103880761-A | Method for synthesizing 4(3H)-quinazolinone derivative by using cyclization elimination one-pot method | UNIV TIANJIN | 2014-06-25 | — | — | CN | disclosed |
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |