Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829907 | 0.93 | CYP1A2 (0.37) | P2RX7 | |
| SCHEMBL17829911 | 0.92 | CTNNB1 (0.39) | CDK9MAPT | |
| SCHEMBL17833270 | 0.91 | CTNNB1 (0.34) | CDK9P2RX7 | |
| SCHEMBL17829829 | 0.90 | POLB (0.41) | HTR6MAOBCDK9 | |
| SCHEMBL17833195 | 0.87 | CYP1A2 (0.39) | CDK9 | |
| SCHEMBL17833267 | 0.84 | CTNNB1 (0.38) | — | |
| SCHEMBL17833193 | 0.84 | SRC (0.38) | CDK9MAPT | |
| SCHEMBL17829569 | 0.83 | POLB (0.45) | — | |
| SCHEMBL17833190 | 0.82 | CYP1A2 (0.48) | PDE5A | |
| SCHEMBL17833196 | 0.81 | MAPK1 (0.38) | CDK9PDE5AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |