Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | STK17B | O94768 | 2/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829911 | 0.91 | CTNNB1 (0.39) | CTNNB1TCF7L2FYNSRCFLT3 | |
| SCHEMBL17833270 | 0.86 | CTNNB1 (0.34) | CTNNB1TCF7L2SRCMEN1KMT2A | |
| SCHEMBL17829907 | 0.85 | CYP1A2 (0.37) | CTNNB1TCF7L2HRH1ALDH1A1CYP1A2 | |
| SCHEMBL17833273 | 0.84 | HTR6 (0.36) | — | |
| SCHEMBL17829569 | 0.83 | POLB (0.45) | CTNNB1TCF7L2FLT3MEN1KMT2A | |
| SCHEMBL17829829 | 0.82 | POLB (0.41) | FLT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL17833195 | 0.78 | CYP1A2 (0.39) | FYNSRCMEN1KMT2APOLB | |
| SCHEMBL17833193 | 0.77 | SRC (0.38) | FYNSRCFLT3POLBALDH1A1 | |
| SCHEMBL17829906 | 0.76 | POLB (0.43) | FLT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL17829909 | 0.76 | P2RX7 (0.38) | CTNNB1TCF7L2POLBALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |