Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829860 | 0.90 | KCNH2 (0.47) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17833283 | 0.86 | SYK (0.40) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17833161 | 0.84 | KMT2A (0.40) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17833238 | 0.82 | TNKS (0.41) | KMT2AKDM4EALDH1A1SYKKCNH2 | |
| SCHEMBL17833235 | 0.82 | SYK (0.43) | KMT2AKDM4EALDH1A1SYKMAPK1 | |
| SCHEMBL17833279 | 0.82 | CTNNB1 (0.37) | KMT2AKDM4EALDH1A1SYKKCNH2 | |
| SCHEMBL17833280 | 0.82 | SYK (0.37) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17829892 | 0.80 | MAPT (0.53) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17829910 | 0.80 | SYK (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17829862 | 0.79 | CCR4 (0.44) | KDM4EALDH1A1TSHRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |