Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13552393 | 0.84 | EGLN1 (0.63) | EGLN1GAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11596790 | 0.82 | EGLN1 (0.61) | EGLN1ACHEKDM4E | |
| SCHEMBL2032859 | 0.82 | EGLN1 (0.61) | EGLN1ACHEKDM4E | |
| SCHEMBL12495312 | 0.82 | EGLN1 (0.65) | EGLN1GAAALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL1912783 | 0.80 | EGLN1 (0.59) | EGLN1ACHE | |
| SCHEMBL18884874 | 0.79 | EGLN1 (0.57) | EGLN1GAASMN1; SMN2MAPTHTT | |
| SCHEMBL17833305 | 0.79 | EPHX1 (0.45) | GAASMN1; SMN2MAPTACHENPC1 | |
| SCHEMBL9408944 | 0.79 | EGLN1 (0.57) | EGLN1ACHE | |
| SCHEMBL24873009 | 0.78 | EGLN1 (0.61) | EGLN1GAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2487820 | 0.77 | EPHX1 (0.57) | EGLN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094199-A1 | COMPOUNDS COMPRISING MODIFIED DIORGANOSILOXANE POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-06-16 | — | — | WO | disclosed |