Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858080 | 0.79 | MMP1 (0.52) | EPHX1EPHX2PAOXNPC1GAA | |
| SCHEMBL17833299 | 0.79 | EGLN1 (0.56) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18902915 | 0.78 | KDM4E (0.37) | EPHX2PAOXSMN1; SMN2MEN1KMT2A | |
| SCHEMBL19705840 | 0.76 | KDM4E (0.61) | PAOXSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18808374 | 0.76 | EPHX1 (0.50) | EPHX1PAOXMMP1MMP2MMP3 | |
| SCHEMBL6129741 | 0.74 | EPHX1 (0.61) | EPHX1EPHX2MMP2PLA2G2ACASP2 | |
| SCHEMBL15336996 | 0.74 | KDM4E (0.36) | EPHX1PAOXSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14822840 | 0.72 | EPHX1 (0.55) | EPHX1GAAMEN1KMT2AACHE | |
| SCHEMBL3257790 | 0.72 | EPHX1 (0.68) | EPHX1EPHX2PLA2G2APLA2G4AMEN1 | |
| SCHEMBL6940482 | 0.72 | MMP1 (0.46) | EPHX1EPHX2PAOXNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094199-A1 | COMPOUNDS COMPRISING MODIFIED DIORGANOSILOXANE POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-06-16 | — | — | WO | disclosed |