Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 3/20 | 0.70 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 10/20 | 0.49 |
| ▸ | KDR | P35968 | 6/20 | 0.48 |
| ▸ | RET | P07949 | 5/20 | 0.48 |
| ▸ | KIF5B | P33176 | 4/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.45 |
| ▸ | GAK | O14976 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | STK10 | O94804 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323445 | 0.82 | JAK3 (1.00) | JAK3MKNK1ABCB1ABCG2EGFR | |
| SCHEMBL30925305 | 0.82 | JAK3 (1.00) | JAK3MKNK1ABCB1ABCG2EGFR | |
| Hydrochloric Acid SCHEMBL6182238 | 0.80 | RET (0.57) | EGFRKDRRETKIF5BLMNA | |
| SCHEMBL28421695 | 0.78 | ABCG2 (0.64) | JAK3MKNK1ABCG2EGFRKDR | |
| SCHEMBL3682274 | 0.76 | FGFR1 (0.70) | EGFRKDRRETKIF5BHTT | |
| SCHEMBL15070939 | 0.76 | EGFR (0.71) | MKNK1ABCG2EGFRKDRMAPT | |
| SCHEMBL5864733 | 0.72 | JAK3 (0.79) | JAK3MKNK1ABCB1ABCG2EGFR | |
| SCHEMBL15496540 | 0.71 | EGFR (0.54) | JAK3MKNK1ABCB1ABCG2EGFR | |
| SCHEMBL8986212 | 0.71 | CYP1A2 (0.54) | EGFRKDRLMNAMAPTHTT | |
| SCHEMBL17532922 | 0.70 | EGFR (0.72) | MKNK1EGFRLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | MEDA AB (SE) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | LIPA, HRH2, HRH1 | JAK3 565/4885MKNK1 4705/4885ABCB1 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.