Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.70 |
| ▸ | FLT1 | P17948 | 2/20 | 0.70 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.70 |
| ▸ | RET | P07949 | 1/20 | 0.70 |
| ▸ | CDK2 | P24941 | 1/20 | 0.70 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.70 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.70 |
| ▸ | KIF5B | P33176 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | RAF1 | P04049 | 11/20 | 0.66 |
| ▸ | BRAF | P15056 | 11/20 | 0.66 |
| ▸ | EGFR | P00533 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077863 | 0.86 | RAF1 (0.74) | FGFR1FLT1TTBK1RETCDK2 | |
| SCHEMBL5569022 | 0.85 | HTT (0.72) | FGFR1FLT1TTBK1RETCDK2 | |
| SCHEMBL15077873 | 0.84 | RAF1 (0.76) | FGFR1FLT1TTBK1RETCDK2 | |
| SCHEMBL17532922 | 0.83 | EGFR (0.72) | GLAHTTRAF1EGFR | |
| SCHEMBL15070939 | 0.83 | EGFR (0.71) | EPHB2KDREGFR | |
| SCHEMBL30249695 | 0.83 | KDR (1.00) | FGFR1FLT1TTBK1RETCDK2 | |
| SCHEMBL29435034 | 0.83 | KDR (1.00) | FGFR1FLT1TTBK1RETCDK2 | |
| SCHEMBL1180103 | 0.83 | KDR (1.00) | FGFR1FLT1TTBK1RETCDK2 | |
| Hydrochloric Acid SCHEMBL6184184 | 0.82 | EGFR (0.71) | GLAHTTRAF1EGFR | |
| Hydrochloric Acid SCHEMBL30433676 | 0.82 | NOD1 (1.00) | FGFR1FLT1TTBK1RETCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781423-B2 | Compounds to promote regeneration of bone marrow | CANCURE LABORATORIES, LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20090004136-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | ZOLTAN LABORATORIES LLC (US) | 2009-01-01 | — | — | US | disclosed |
| WO-2008118164-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | ZOLTAN LABORATORIES LLC (US) | 2008-10-02 | — | — | WO | disclosed |
| US-20080234234-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | ZOLTAN LABORATORIES, LLC (US) | 2008-09-25 | — | — | US | disclosed |
| US-7423029-B1 | from endogenous or exogenous stem/progenitor cells and to normalize blood cell and platelet counts; e.g. [3-(3,4-dimethyl-9-oxo-9H-thioxanthen-2-yloxy)-2-hydroxypropyl]trimethylammonium chloride; antitumor and AIDS agent; low toxicity, side effect reduction | ZOLTAN LABORATORIES, LLC (US) | 2008-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090004136-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | PDGFA, BMP4, BMP2 | FGFR1 947/4885FLT1 532/4885TTBK1 743/4885 |
| US-20080234234-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | PDGFA, BMP4, BMP2 | FGFR1 947/4885FLT1 532/4885TTBK1 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.