Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729532 | 1.00 | POLG (0.43) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL13314154 | 0.91 | POLG (0.47) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL6229380 | 0.89 | POLG (0.46) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL6229367 | 0.89 | POLG (0.46) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL10022231 | 0.89 | P2RY2 (0.40) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL10020460 | 0.89 | P2RY2 (0.40) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL7661079 | 0.88 | POLG (0.43) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL13314155 | 0.86 | POLG (0.41) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL20417318 | 0.85 | POLG (0.41) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL20417310 | 0.85 | POLG (0.41) | POLGP2RY2P2RY4P2RY6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |