Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229367 | 1.00 | POLG (0.46) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL20417310 | 0.93 | POLG (0.41) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL20417318 | 0.93 | POLG (0.41) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL13314154 | 0.93 | POLG (0.47) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL30083115 | 0.90 | POLG (0.47) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL17833854 | 0.89 | POLG (0.43) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL7661079 | 0.89 | POLG (0.43) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL12729532 | 0.89 | POLG (0.43) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL22327108 | 0.88 | POLG (0.51) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL5664015 | 0.88 | POLG (0.51) | POLGPOLBP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112254-A4 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PROD INC (US) | 2005-03-16 | — | — | EP | disclosed |
| US-6437141-B2 | FOR LABELING TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-20010020098-A1 | For labeling target molecules | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-09-06 | — | — | US | disclosed |
| EP-1112254-A2 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN Life Science Products, Inc. (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6224644-B1 | CYANINE DYES INCLUDES FREE OR PROTECTED THIOL, AMINE OR HYDROXY SUBSTITUENT CAPABLE OF REACTING WITH A TARGET MOLECULE THROUGH A NEUCLOPHILIC DISPLACEMENT, USEFUL IN LABELING A VARIETY OF TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6204389-B1 | DEBLOCKING; NUCLEOPHILIC DISPLACEMENT | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6197956-B1 | FLUORESCENT BENZIMIDAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, BENZOTHIAZINE, BENZOXAZINE AND QUINOLINE DYES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-06 | — | — | US | disclosed |
| WO-2000063296-A2 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-10-26 | — | — | WO | disclosed |
| US-6114350-A | Cyanine dyes and synthesis methods thereof | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020098-A1 | For labeling target molecules | CYC1, THEM6, TPH1 | POLG 3325/4885POLB 4265/4885P2RY2 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.