Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.41 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | DTYMK | P23919 | 4/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729519 | 0.95 | POLB (0.43) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL12729465 | 0.87 | POLB (0.49) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL17833850 | 0.87 | POLB (0.49) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL12729514 | 0.83 | POLB (0.53) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL12729595 | 0.82 | POLB (0.45) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL205857 | 0.77 | POLB (0.58) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL30848914 | 0.77 | POLB (0.58) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL12729466 | 0.77 | POLB (0.52) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL17833848 | 0.77 | POLB (0.52) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL4820794 | 0.74 | NT5E (0.67) | POLBP2RY6P2RY2P2RY4NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |