Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585487 | 0.89 | TSHR (0.67) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL11427481 | 0.86 | — | — | |
| SCHEMBL11432968 | 0.82 | TSHR (0.64) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL628936 | 0.82 | — | — | |
| SCHEMBL20634408 | 0.81 | TSHR (0.72) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL11613489 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL11612260 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL18811280 | 0.80 | TSHR (0.45) | TSHRLMNAALDH1A1KDM4ERECQL | |
| SCHEMBL14353413 | 0.79 | TSHR (0.67) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7261779 | 0.77 | ALDH1A1 (0.39) | TSHRLMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |