⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16543887 | 0.76 | — | — | |
| SCHEMBL20734016 | 0.67 | — | — | |
| SCHEMBL16543884 | 0.66 | HDAC1 (0.51) | — | |
| SCHEMBL6895559 | 0.64 | — | — | |
| SCHEMBL13848641 | 0.64 | BRD4 (0.43) | — | |
| SCHEMBL6331422 | 0.62 | MAPT (0.55) | — | |
| SCHEMBL17833976 | 0.62 | MAPT (0.37) | — | |
| SCHEMBL17833971 | 0.62 | MEN1 (0.32) | — | |
| SCHEMBL23894741 | 0.62 | GSK3A (0.38) | — | |
| SCHEMBL7945735 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017520-B2 | Myc modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-07-10 | — | — | US | disclosed |
| US-20160168165-A1 | MYC MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |