Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | INMT | O95050 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19481284 | 0.76 | INMT (0.38) | BRD4BRD2INMT | |
| SCHEMBL17459703 | 0.75 | INMT (0.33) | INMTMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL17459701 | 0.75 | INMT (0.33) | INMTMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL12640776 | 0.71 | INMT (0.44) | BRD4BRD2INMTMEN1MAPT | |
| SCHEMBL10735746 | 0.70 | MAPT (0.47) | MEN1MAPTKMT2AGAARAB9A | |
| SCHEMBL17459688 | 0.69 | BRD4 (0.35) | BRD4MEN1MAPTKMT2ARAB9A | |
| SCHEMBL17459686 | 0.69 | BRD4 (0.35) | BRD4MEN1MAPTKMT2ARAB9A | |
| SCHEMBL4827581 | 0.69 | RAB9A (0.39) | MEN1MAPTKMT2AGAARAB9A | |
| SCHEMBL1076577 | 0.69 | ALDH1A1 (0.41) | MEN1MAPTKMT2ARAB9AALDH1A1 | |
| SCHEMBL6387239 | 0.69 | ALDH1A1 (0.41) | MEN1MAPTKMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131481-A1 | Transcription Factor Modulating Compounds and Methods of Use Thereof | PARATEK PHARMACEUTICALS, INC. (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131481-A1 | Transcription Factor Modulating Compounds and Methods of Use Thereof | CREBBP, JUN, IRF3 | BRD4 109/4885BRD2 227/4885INMT 1439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.