Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 11/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24484640 | 0.86 | DGAT1 (0.47) | DGAT1NPC1RAB9APAX8APP | |
| SCHEMBL15037358 | 0.84 | DGAT1 (0.46) | DGAT1TLR8KDM4EALDH1A1MAPT | |
| SCHEMBL27338948 | 0.84 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL31351735 | 0.81 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL9936783 | 0.79 | DGAT1 (0.77) | DGAT1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL67976 | 0.79 | DGAT1 (0.50) | DGAT1NPC1RAB9ATLR8 | |
| SCHEMBL16661146 | 0.79 | DGAT1 (0.66) | DGAT1TLR8 | |
| SCHEMBL22478638 | 0.79 | DGAT1 (0.43) | DGAT1NPC1RAB9APAX8TLR8 | |
| SCHEMBL15293920 | 0.77 | DGAT1 (0.64) | DGAT1 | |
| SCHEMBL19065558 | 0.76 | DGAT1 (0.46) | DGAT1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |