Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.46 |
| ▸ | ADCY6 | O43306 | 5/20 | 0.45 |
| ▸ | ADCY3 | O60266 | 5/20 | 0.45 |
| ▸ | ADCY9 | O60503 | 5/20 | 0.45 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.45 |
| ▸ | ADCY8 | P40145 | 5/20 | 0.45 |
| ▸ | ADCY7 | P51828 | 5/20 | 0.45 |
| ▸ | ADCY2 | Q08462 | 5/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 5/20 | 0.45 |
| ▸ | ADCY4 | Q8NFM4 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | GCG | P01275 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305538 | 0.93 | L3MBTL1 (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16306150 | 0.90 | GCGR (0.54) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL17995158 | 0.89 | GCGR (0.49) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16305819 | 0.88 | GCGR (0.53) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16305825 | 0.88 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16380079 | 0.88 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16305921 | 0.88 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL15019653 | 0.88 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL15019651 | 0.88 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16305923 | 0.86 | GCGR (0.51) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |