SCHEMBL17834708

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22384089	1.00	CTSS (0.47)	CTSSCTSKTDP1CTSBMAPT
	SCHEMBL22384302	0.90	CTSS (0.47)	CTSSCTSKTDP1MAPTPOLB
	SCHEMBL17834705	0.90	CTSS (0.47)	CTSSCTSKTDP1MAPTPOLB
	SCHEMBL22167206	0.89	TDP1 (0.41)	CTSSCTSKTDP1CTSBMAPT
	SCHEMBL17459587	0.89	TDP1 (0.41)	CTSSCTSKTDP1CTSBMAPT
	SCHEMBL16305782	0.89	TDP1 (0.41)	CTSSCTSKTDP1CTSBMAPT
	SCHEMBL17459588	0.89	TDP1 (0.41)	CTSSCTSKTDP1CTSBMAPT
	SCHEMBL17968786	0.88	MME (0.47)	CTSSCTSKCTSBMME
	SCHEMBL22384088	0.85	CTSS (0.53)	CTSSCTSKTDP1CTSBMAPT
	SCHEMBL22756207	0.83	TDP1 (0.39)	CTSSCTSKTDP1CTSBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.