Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.33 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.33 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.33 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.33 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.33 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.33 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834588 | 0.95 | MME (0.36) | MMEANPEPEGLN1EGLN3 | |
| SCHEMBL17834772 | 0.95 | MME (0.39) | MMEANPEPEGLN1EGLN3 | |
| SCHEMBL16306201 | 0.93 | MME (0.38) | MMEANPEPEGLN1EGLN3PSMB10 | |
| SCHEMBL17834615 | 0.93 | ACE (0.39) | MMEANPEPEGLN1EGLN3PSMB10 | |
| SCHEMBL17834445 | 0.93 | KIFC1 (0.37) | MMEECE1 | |
| SCHEMBL17834582 | 0.92 | MME (0.37) | MMEANPEPEGLN1EGLN3PSMB10 | |
| SCHEMBL17834584 | 0.91 | MME (0.36) | MMEANPEPEGLN1EGLN3 | |
| SCHEMBL17834589 | 0.91 | MME (0.36) | MMEANPEPEGLN1EGLN3 | |
| SCHEMBL19485617 | 0.91 | MME (0.36) | MMEANPEPEGLN1EGLN3 | |
| SCHEMBL17834602 | 0.91 | MME (0.36) | MMEANPEPEGLN1EGLN3PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10034886-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2018-07-31 | — | — | US | disclosed |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2018-01-25 | — | — | US | disclosed |
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-08-11 | — | — | US | disclosed |
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | MME 796/4885ANPEP 305/4885EGLN1 1623/4885 |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | MME 796/4885ANPEP 305/4885EGLN1 1623/4885 |
| US-10034886-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | MME 919/4885ANPEP 407/4885EGLN1 1389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.