Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998982 | 0.98 | PDK2 (0.40) | PDK2PGRALKDYRK3CLK1 | |
| SCHEMBL15183583 | 0.92 | PDK2 (0.44) | PDK2PGRGABRA1GABRG2GABRB3 | |
| SCHEMBL15290086 | 0.90 | PDK2 (0.36) | PDK2 | |
| SCHEMBL16998976 | 0.89 | PDK2 (0.41) | PDK2PGRGABRA1GABRG2GABRB3 | |
| SCHEMBL808085 | 0.89 | PGR (0.41) | PDK2PGR | |
| SCHEMBL19754291 | 0.88 | PDK2 (0.45) | PDK2PGRGABRA1GABRG2GABRB3 | |
| SCHEMBL16998979 | 0.88 | PDK2 (0.39) | PDK2PGRALKDYRK3CLK1 | |
| SCHEMBL21442823 | 0.88 | PDK2 (0.41) | PDK2PGRADORA2AADORA2BADORA1 | |
| SCHEMBL20618642 | 0.88 | PDK2 (0.37) | PDK2PGRALKDYRK3CLK1 | |
| SCHEMBL17835032 | 0.88 | PDK2 (0.39) | PDK2PGRGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683453-B2 | Organic compounds with soluble groups | MERCK PATENT GMBH (DE) | 2020-06-16 | — | — | US | disclosed |
| US-20170369773-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | UDC IRELAND LIMITED (IE) | 2017-12-28 | — | — | US | disclosed |
| WO-2016091353-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | MERCK PATENT GMBH (DE) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369773-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | SLCO4C1, SLCO1B3, SLCO2B1 | PDK2 2619/4885PGR 1042/4885ALK 86/4885 |
| US-10683453-B2 | Organic compounds with soluble groups | SLCO4C1, SLCO1B3, SLCO2B1 | PDK2 2619/4885PGR 1042/4885ALK 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.