Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068420 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E | |
| SCHEMBL16186691 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E | |
| SCHEMBL15030704 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E | |
| SCHEMBL17955172 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E | |
| SCHEMBL1168198 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E | |
| SCHEMBL30282355 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E | |
| SCHEMBL15377824 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E | |
| SCHEMBL16684030 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E | |
| SCHEMBL16742271 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E | |
| SCHEMBL18916874 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPK1L3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683453-B2 | Organic compounds with soluble groups | MERCK PATENT GMBH (DE) | 2020-06-16 | — | — | US | disclosed |
| EP-3230403-B1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | MERCK PATENT GMBH (DE) | 2019-10-09 | — | — | EP | disclosed |
| US-20170369773-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | UDC IRELAND LIMITED (IE) | 2017-12-28 | — | — | US | disclosed |
| WO-2016091353-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | MERCK PATENT GMBH (DE) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369773-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | SLCO4C1, SLCO1B3, SLCO2B1 | ALDH1A1 332/4885MAPK1 3165/4885L3MBTL1 3504/4885 |
| US-10683453-B2 | Organic compounds with soluble groups | SLCO4C1, SLCO1B3, SLCO2B1 | ALDH1A1 332/4885MAPK1 3165/4885L3MBTL1 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.