Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531161 | 0.84 | RAF1 (0.46) | LMNARAF1PLA2G7GAABRAF | |
| SCHEMBL38882 | 0.83 | NPSR1 (0.39) | LMNAP2RX7ALOX15NPSR1KDM4E | |
| SCHEMBL1531398 | 0.80 | MRGPRX4 (0.40) | LMNACYP1A2CYP2C19F2PRSS1 | |
| SCHEMBL38481 | 0.80 | NPSR1 (0.37) | LMNAP2RX7ALOX15NPSR1KDM4E | |
| SCHEMBL1531155 | 0.78 | NPSR1 (0.39) | LMNAALOX15NPSR1PLA2G7GAA | |
| SCHEMBL1531228 | 0.76 | BRAF (0.40) | RAF1NPSR1KDM4EPLA2G7GAA | |
| SCHEMBL1531072 | 0.76 | TDP1 (0.37) | LMNAALOX15NPSR1GAAMAPT | |
| SCHEMBL1531195 | 0.76 | LMNA (0.48) | LMNACYP1A2CYP2C19MAPT | |
| SCHEMBL13406386 | 0.75 | GAA (0.39) | RAF1ALOX15NPSR1KDM4EGAA | |
| SCHEMBL1531129 | 0.75 | ASAH1 (0.41) | LMNAP2RX7ALOX15NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3033426-A2 | PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES | BASF Agro B.V. (NL) | 2016-06-22 | — | — | EP | disclosed |