Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | FABP2 | P12104 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903707 | 0.91 | USP2 (0.40) | GPR84CYP2D6ANPEPLAP3LMNA | |
| SCHEMBL2135416 | 0.80 | USP2 (0.37) | GPR84ANPEPLAP3LMNAMAPT | |
| SCHEMBL3290537 | 0.79 | USP2 (0.41) | GPR84CYP2D6ANPEPLAP3LMNA | |
| SCHEMBL704337 | 0.77 | CYP2D6 (0.36) | CYP2D6MAPTUSP2MEN1KMT2A | |
| SCHEMBL7895673 | 0.74 | INPPL1 (0.46) | GPR84LMNAMAPTUSP2MAPK1 | |
| SCHEMBL30473235 | 0.72 | KDM4E (0.46) | GPR84LMNAMAPTUSP2HTT | |
| SCHEMBL7642864 | 0.72 | KDM4E (0.46) | GPR84LMNAMAPTUSP2HTT | |
| SCHEMBL8758997 | 0.72 | BACE1 (0.43) | HPGDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29666357 | 0.71 | KDM4E (0.40) | GPR84USP2S1PR1PTPN5HPGD | |
| SCHEMBL28931611 | 0.71 | SRC (0.42) | GPR84ANPEPLAP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034532-B1 | POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION, MOLDED ARTICLE, SLIDING-PROPERTIES IMPROVEMENT AGENT, AND SLIDING MEMBER | MITSUBISHI CHEM CORP (JP) | 2019-11-06 | — | — | EP | disclosed |
| EP-3375800-A1 | POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION, MOLDED ARTICLE, SLIDING-PROPERTIES IMPROVEMENT AGENT, AND SLIDING MEMBER | Mitsubishi Chemical Corporation (JP) | 2018-09-19 | — | — | EP | disclosed |
| US-9765170-B2 | Graft copolymer containing polyorganosiloxane, resin composition, molded article, slidability-improving agent, and sliding member | MITSUBISHI CHEMICAL CORPORATION (JP) | 2017-09-19 | — | — | US | disclosed |
| US-20160194428-A1 | GRAFT COPOLYMER CONTAINING POLYORGANOSILOXANE, RESIN COMPOSITION, MOLDED ARTICLE, SLIDABILITY-IMPROVING AGENT, AND SLIDING MEMBER | MITSUBISHI RAYON CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |
| EP-3034532-A2 | POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION, MOLDED ARTICLE, SLIDING-PROPERTIES IMPROVEMENT AGENT, AND SLIDING MEMBER | Mitsubishi Rayon Co., Ltd. (JP) | 2016-06-22 | — | — | EP | disclosed |